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1

A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates

Hannu Mönkkönen, Seppo Auriola, Petri Lehenkari, Maarit Kellinsalmi, Ilmo E Hassinen, Jouko Vepsäläinen, Jukka Mönkkönen

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

2

Determination of metformin and its prodrugs in human and rat blood by hydrophilic interaction liquid chromatography

Kristiina M. Huttunen, Jarkko Rautio, Jukka Leppänen, Jouko Vepsäläinen, Pekka Keski-Rahkonen

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2009

Language:

english

File:

PDF, 299 KB

english, 2009

3

Synthesis of anhydro psicofuranosyl nucleosides

Jarkko Roivainen, Jouko Vepsäläinen, Alex Azhayev, Igor A. Mikhailopulo

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 74 KB

english, 2002

4

Synthesis of a water-soluble prodrug of entacapone

Jukka Leppänen, Juhani Huuskonen, Jouko Savolainen, Tapio Nevalainen, Hannu Taipale, Jouko Vepsäläinen, Jukka Gynther, Tomi Järvinen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 115 KB

english, 2000

5

Mimetics of the disulfide bridge between the N- and C-terminal cysteines of the KLK3-stimulating peptide B-2

Miikka Pakkala, Janne Weisell, Can Hekim, Jouko Vepsäläinen, Erik A. A. Wallen, Ulf-Håkan Stenman, Hannu Koistinen, Ale Närvänen

Journal:

Year:

2010

Language:

english

File:

PDF, 384 KB

english, 2010

6

Synthesis, in vitro and in vivo characterization of novel ethyl dioxy phosphate prodrug of propofol

Hanna Kumpulainen, Tomi Järvinen, Anne Mannila, Jukka Leppänen, Tapio Nevalainen, Antti Mäntylä, Jouko Vepsäläinen, Jarkko Rautio

Journal:

European Journal of Pharmaceutical Sciences

Year:

2008

Language:

english

File:

PDF, 444 KB

english, 2008

7

A novel bisphosphonate-based solid phase method for effective removal of chromium(iii) from aqueous solutions and tannery effluents

Alanne, Aino-Liisa, Tuikka, Matti, Tõnsuaadu, Kaia, Ylisirniö, Markku, Hämäläinen, Lea, Turhanen, Petri, Vepsäläinen, Jouko, Peräniemi, Sirpa

Journal:

Year:

2013

Language:

english

File:

PDF, 532 KB

english, 2013

8

Synthesis and bioactivity studies of Mannich bases derived from acetophenone

Gul, Halise Inci, Vepsäläinen, Jouko, Gul, Mustafa, Ojanen, Tarja, Hänninen, Osmo

Journal:

Pathophysiology

Year:

1998

Language:

english

File:

PDF, 146 KB

english, 1998

9

Assessing the response of plant flavonoids to UV radiation: an overview of appropriate techniques

Julkunen-Tiitto, Riitta, Nenadis, Nikolaos, Neugart, Susanne, Robson, Matthew, Agati, Giovanni, Vepsäläinen, Jouko, Zipoli, Gaetano, Nybakken, Line, Winkler, Barbro, Jansen, Marcel A. K.

Journal:

Phytochemistry Reviews

Year:

2015

Language:

english

File:

PDF, 824 KB

english, 2015

10

Synthesis of Novel Fatty Acid Derivatives of Etidronic Acid

Turhanen, Petri A., Vepsäläinen, Jouko J.

Journal:

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

11

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

Tynkkynen, Tuulia, Wang, Qin, Ekholm, Jussi, Anufrieva, Olga, Ohukainen, Pauli, Vepsäläinen, Jouko, Männikkö, Minna, Keinänen-Kiukaanniemi, Sirkka, Holmes, Michael V, Goodwin, Matthew, Ring, Susan, Ch

Journal:

International Journal of Epidemiology

Year:

2019

Language:

english

File:

PDF, 2.30 MB

english, 2019

12

Green and Efficient Esterification Method Using Dried Dowex H + /NaI Approach

Turhanen, Petri A., Leppänen, Jukka, Vepsäläinen, Jouko J.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.50 MB

english, 2019

13

Complete Spectral Analysis of the 1H NMR 16-Spin System of β-Pinene

Erkki Kolehmainen, Katri Laihia, Reino Laatikainen, Jouko Vepsäläinen, Matthias Niemitz, Reijo Suontamo

Journal:

Magnetic Resonance in Chemistry

Year:

1997

Language:

english

File:

PDF, 323 KB

english, 1997

14

Characterization of a conformationally flexible system: NMR spectroscopic study of 1,5-diphenylpentane-2,4-dione

Juha T. Pulkkinen, Reino Laatikainen, Jouko J. Vepsäläinen, Markku J. Ahlgrén

Journal:

Magnetic Resonance in Chemistry

Year:

1999

Language:

english

File:

PDF, 171 KB

english, 1999

15

Preparation of [18F]β-CFT-FP and [11C]β-CFT-FP, selective radioligands for visualisation of the dopamine transporter using positron emission tomography (PET)

Eeva-Liisa Kämäräinen, Teija Kyllönen, Anu Airaksinen, Camilla Lundkvist, Meixiang Yu, Kjell Någren, Johan Sandell, Oliver Langer, Jouko Vepsäläinen, Jukka Hiltunen, Kim Bergström, Simo Lötjönen, Timo

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2000

File:

PDF, 1.99 MB

2000

16

ChemInform Abstract: Effect of Acetophenone Derived Mannich Bases (I) on Cellular Glutathione Level in Jurkat Cells — A Possible Mechanism of Action.

Mustafa Gul, Halise Inci Gul, Jouko Vepsalainen, Ercin Erciyas, Osmo Hanninen

Journal:

Year:

2001

File:

PDF, 28 KB

2001

17

One-Pot Synthesis of 3,4-Disubstituted 1H-Pyrroles from 2-Tropanones.

Anu J. Airaksinen, Markku Ahlgren, Jouko Vepsalainen

Journal:

Year:

2002

File:

PDF, 28 KB

2002

18

Synthesis and Evaluation of Anticonvulsant Activities of Some Bis Mannich Bases and Corresponding Piperidinols.

Halise Inci Gul, Unsal Calis, Jouko Vepsalainen

Journal:

Year:

2003

File:

PDF, 93 KB

2003

19

Synthesis of Some Mono-Mannich Bases and Corresponding Azine Derivatives and Evaluation of Their Anticonvulsant Activity.

Halise Inci Gul, Jouko Vepsalainen

Journal:

Year:

2004

File:

PDF, 11 KB

2004

20

A Structural Study of Bisphosphonate Metal Complexes − Three New Polymeric Structures of the Calcium Complex of Clodronic Acid

Mervi Kontturi, Sirpa Peräniemi, Jouko J. Vepsäläinen, Markku Ahlgrén

Journal:

European Journal of Inorganic Chemistry

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

21

Syntheses, X-ray Diffraction Study and Characterisations of Ni and Zn Complexes of Clodronic Acid and Its Dibenzoyl Derivative

Susan Kunnas-Hiltunen, Matti Haukka, Jouko Vepsäläinen, Markku Ahlgrén

Journal:

European Journal of Inorganic Chemistry

Year:

2009

Language:

english

File:

PDF, 1.26 MB

english, 2009

22

Bisphosphonic compounds. I. Preparation of 13C- and 14C-labelled clodronate

Vepsäläinen Jouko, Nupponen Heikki, Pohjala Esko

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1991

Language:

english

File:

PDF, 229 KB

english, 1991

23

Radiosynthesis of [123I]N-(3-iodoprop-(2E)-enyl)-2α-(imino-methyl)-3β-(3′,4′-dichlorophenyl) nortropane as a potential SPET tracer for dopamine transporter

Meixiang Yu, Anu J. Airaksinen, Antony D. Gee, Simo Lötjönen, Jyrki T. Kuikka, Jouko J. Vepsäläinen, Jukka Hiltunen, Kim A. Bergström

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

24

Simplified synthesis of N-(3-[18F]fluoropropyl)-2β-carbomethoxy-3β-(4-fluorophenyl)nortropane ([18F]β-CFT-FP) using [18F]fluoropropyl tosylate as the labelling reagent

Teija Koivula, Outi Perhola, Eeva-Liisa Kämäräinen, Tiina Lipponen, Jouko Vepsäläinen, Olof Solin

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2005

Language:

english

File:

PDF, 114 KB

english, 2005

25

Comparison of enzymatic hydrolysis of pilocarpine prodrugs in human plasma, rabbit cornea, and butyrylcholinesterase solutions

Tomi Järvinen, Minna Poikolainen, Pekka Suhonen, Jouko Vepsäläinen, Sakari Alaranta, Arto Urtti

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 645 KB

english, 1995

26

1H and 13C NMR studies on nitrosonaphthols, and their complexation with the dioxouranium(VI) ion

Anto Vainiotalo, Jouko Vepsäläinen

Journal:

Magnetic Resonance in Chemistry

Year:

1986

Language:

english

File:

PDF, 434 KB

english, 1986

27

General Strategies for Total-Lineshape-Type Spectral Analysis of NMR Spectra Using Integral-Transform Iterator

Reino Laatikainen, Matthias Niemitz, Ursula Weber, Jukka Sundelin, Tommi Hassinen, Jouko Vepsäläinen

Journal:

Journal of Magnetic Resonance, Series A

Year:

1996

Language:

english

File:

PDF, 209 KB

english, 1996

28

Isolation and structure determination of three triterpenes from bark resin of juvenile european white birch

Hannu T. Taipale, Jouko Vepsäläinen, Reino Laatikainen, Paul B. Reichardt, Seppo P. Lapinjoki

Journal:

Year:

1993

Language:

english

File:

PDF, 572 KB

english, 1993

29

An improved synthetic method and the first crystal structures for (dihalomethylene)bisphosphonate partial esters

Jouko J. Vepsäläinen, Jussi Kivikoski, Markku Ahlgrén, Heikki E. Nupponen, Esko K. Pohjala

Journal:

Year:

1995

Language:

english

File:

PDF, 866 KB

english, 1995

30

Synthesis of hydroxylamine analogues of polyamines

Alex R Khomutov, Jouko J Vepsäläinen, Alexander S Shvetsov, Tapani Hyvönen, Tuomo A Keinänen, Vladimir N Pustobaev, Terho O Eloranta, Radii M Khomutov

Journal:

Year:

1996

Language:

english

File:

PDF, 922 KB

english, 1996

31

A general route to 3-unsubstituted 1,5-diaryl-2,4-pentanediones and -4-Methoxy-2-pentanones

Juha Pulkkinen, Jouko Vepsäläinen, Reino Laatikainen

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 152 KB

english, 1994

32

Bisphosphonic compounds VIII. A facile and selective one-pot synthesis of P,P-dialkyl (dichloromethylene)bisphosphonate partial esters

Jouko Vepsäläinen, Heikki Nupponen, Esko Pohjala

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 206 KB

english, 1996

33

Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives

Antti Mäntylä, Jarkko Rautio, Tapio Nevalainen, Jouko Vepsälainen, Risto Juvonen, Howard Kendrick, Tracy Garnier, Simon L Croft, Tomi Järvinen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 284 KB

english, 2004

34

3-Deazaadenosine analogues of p5′A2′p5′A2′p5′A: synthesis, stereochemistry, and the roles of adenine ring nitrogen-3 in the interaction with RNase L

Elena N Kalinichenko, Tatiana L Podkopaeva, Elena V Budko, Frank Seela, Beihua Dong, Robert Silverman, Jouko Vepsäläinen, Paul F Torrence, Igor A Mikhailopulo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 409 KB

english, 2004

35

Synthesis and identification of pilocarpic acid diesters, prodrugs of pilocarpine

Tomi Järvinen, Seppo Auriola, Pekka Peura, Pekka Suhonen, Arto Urtti, Jouko Vepsäläinen

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1991

Language:

english

File:

PDF, 660 KB

english, 1991

36

Synthesis and analysis of O,O′-dicarboxylate (dibenzyl) bispilocarpates as possible prodrugs of pilocarpine

Tomi Järvinen, Pekka Suhonen, Seppo Auriola, Jouko Vepsäläinen, Arto Urtti, Pekka Peura

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1992

Language:

english

File:

PDF, 711 KB

english, 1992

37

2(S)-(Cycloalk-1-enecarbonyl)-1-(4-phenyl-butanoyl)pyrrolidines and 2(S)-(aroyl)-1-(4-phenylbutanoyl)pyrrolidines as prolyl oligopeptidase inhibitors

Elina M. Jarho, Jarkko I. Venäläinen, Sami Poutiainen, Harri Leskinen, Jouko Vepsäläinen, Johannes A.M. Christiaans, Markus M. Forsberg, Pekka T. Männistö, Erik A.A. Wallén

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 190 KB

english, 2007

38

Synthesis and biological evaluation of 6/7-exo-methyl-3β-(4-iodo)phenyltropane-2β-carboxylic acid methyl esters

Anu J. Airaksinen, Marko Huotari, Alexander Shvetsov, Pirjo Vainiotalo, Pekka T. Männisto, Leena Tuomisto, Kim A. Bergström, Jouko Vepsäläinen

Journal:

European Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 187 KB

english, 2005

39

Analysis of underivatized polyamines by reversed phase liquid chromatography with electrospray tandem mass spectrometry

Merja R. Häkkinen, Tuomo A. Keinänen, Jouko Vepsäläinen, Alex R. Khomutov, Leena Alhonen, Juhani Jänne, Seppo Auriola

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2007

Language:

english

File:

PDF, 686 KB

english, 2007

40

X-ray diffraction study of bisphosphonate metal complexes: Mg and Ca complexes of (dichloromethylene)bisphosphonic acid P,P′-diisopropyl ester

Mervi Kontturi, Sirpa Peräniemi, Jouko J. Vepsäläinen, Markku Ahlgrén

Journal:

Year:

2005

Language:

english

File:

PDF, 356 KB

english, 2005

41

X-ray diffraction study of bisphosphonate metal complexes: Mg, Sr and Ba complexes of (dichloromethylene)bisphosphonic acid P,P′-dibenzoyl anhydride

Susan Kunnas-Hiltunen, Mervi Matilainen, Jouko J. Vepsäläinen, Markku Ahlgrén

Journal:

Year:

2009

Language:

english

File:

PDF, 588 KB

english, 2009

42

Synthesis of novel optical isomers of α-methylpolyamines

Nikolay A. Grigorenko, Alex R. Khomutov, Tuomo A. Keinänen, Aki Järvinen, Leena Alhonen, Juhani Jänne, Jouko Vepsäläinen

Journal:

Year:

2007

Language:

english

File:

PDF, 206 KB

english, 2007

43

Synthesis of novel deuterium labelled derivatives of N-alkylated polyamines

Merja R. Häkkinen, Tuomo A. Keinänen, Alex R. Khomutov, Seppo Auriola, Janne Weisell, Leena Alhonen, Juhani Jänne, Jouko Vepsäläinen

Journal:

Year:

2009

Language:

english

File:

PDF, 626 KB

english, 2009

44

A novel and selective synthesis of di- and trimethylpiperazinium acetic acid iodide salts

Jukka Holappa, Tapio Nevalainen, Rustam Safin, Jouko Vepsäläinen, Tomi Järvinen

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

45

Convenient microwave-assisted synthesis of 1-chloroethyl phosphates

Hanna Kumpulainen, Raimo Saari, Marko Lehtonen, Jarkko Rautio, Tomi Järvinen, Jouko Vepsäläinen

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 81 KB

english, 2006

46

Synthesis and characterization of sodium di-μ-hydroxo-bis[3,6-disulpho-1,2-naphthoquinone-1-oximato-O,N-dioxouranate(VI)]

Anto Vainiotalo, Tuure-Pekka Jauhiainen, Jouko Vepsäläinen, Matti Kauppinen

Journal:

Inorganica Chimica Acta

Year:

1987

Language:

english

File:

PDF, 153 KB

english, 1987

47

Reduction of 6/7-substituted 3-phenyltrop-3-en-2-ones: stereoselectivity and conformational analysis of the products

Anu J Airaksinen, Jarkko Lipsonen, Markku Ahlgren, Pirjo Vainiotalo, Kim A Bergström, Reino Laatikainen, Jouko Vepsäläinen

Journal:

Year:

2003

Language:

english

File:

PDF, 201 KB

english, 2003

48

Strategies for the selective synthesis of monosubstituted (dichloromethylene)bisphosphonate esters

Marko J Ahlmark, Jouko J Vepsäläinen

Journal:

Year:

1997

Language:

english

File:

PDF, 447 KB

english, 1997

49

Nuclear magnetic resonance and molecular orbital study of some cocaine analogues

Anu J. Airaksinen, Kari A. Tuppurainen, Simo E. Lötjönen, Matthias Niemitz, Meixiang Yu, Jouko J. Vepsäläinen, Reino Laatikainen, Jukka Hiltunen, Kim A. Bergström

Journal:

Year:

1999

Language:

english

File:

PDF, 566 KB

english, 1999

50

Novel acid-free cleavage of N-(2-hydroxyarylidene) protected amines

Alex R Khomutov, Alexander S Shvetsov, Jouko J Vepsäläinen, Anatoly M Kritzyn

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 70 KB

english, 2001